BAY-293 |
| Catalog No.GC33186 |
BAY-293, una valiosa sonda quÍmica, bloquea la activaciÓn de RAS a través de la interrupciÓn de la interacciÓn KRAS-SOS1 con un IC50 de 21 nM. BAY-293 es un potente inhibidor de Son of Sevenless 1 (SOS1). SOS1 es el factor de intercambio de nucleÓtidos de guanina (GEF) y activador de RAS.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2244904-70-7
Sample solution is provided at 25 µL, 10mM.
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BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM[1].
[1]. Hillig RC, et al. Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1interaction. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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