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Biotin-PEG4-amine

Catalog No.GC60080

La biotina-PEG4-amina es un conector PROTAC basado en PEG marcado con biotina que se puede utilizar en la sÍntesis de PROTAC.

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Biotin-PEG4-amine Chemical Structure

Cas No.: 663171-32-2

Tamaño Precio Disponibilidad Cantidad
5mg
56,00 $
Disponible
10mg
93,00 $
Disponible
50mg
232,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Biotin-PEG4-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

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