Coenzyme A (lithium salt hydrate) (Synonyms: CoA)

Name: Coenzyme A (lithium salt hydrate)
Brand: GlpBio
SKU: GC47114
Availability: InStock
Rating: 5 (19 reviews)

Catalog No.GC47114

An essential cofactor in enzymatic acetyl transfer reactions

Products are for research use only. Not for human use. We do not sell to patients.

Coenzyme A (lithium salt hydrate) Chemical Structure

Cas No.: N/A

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25 mg	83,00 $	Disponible
50 mg	160,00 $	Disponible
100 mg	302,00 $	Disponible
250 mg	672,00 $	Disponible

Tel：(909) 407-4943 Email: sales@glpbio.com

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

GlpBio Products Cited In Reputable Papers

Nature
610.7931 (2022): 366-372

Nature
618, 1017–1023 (2023)

Cell
183.7 (2020): 1867-1883

Cell Research
31, 1291–1307 (2021)

Cell Research
33, 273–287 (2023)

Cell Research
33, 546–561 (2023)

Molecular Cancer
21.1 (2022): 1-17

Molecular Cancer
21.1 (2022): 1-18

Cancer Cell
39 (2021): 1-16

Cell Host Microbe
30.8 (2022): 1124-1138

Cell Host Microbe
31.5 (2023): 766-780

Cell Host Microbe
31.3 (2023): 418-43

Cell Metabolism
34.2 (2022): 240-255

Ann Rheum Dis
82(4): 533-545 (2023)

Cell Mol Immunol
20, 264–276 (2023)

Adv Funct Mater
33.35 (2023): 2214998

Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >95.00%

Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism.¹ About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP.² The pantothenate kinase step of the CoA biosynthetic pathway has been identified as a target for the development of antibacterial compounds.³

1.Leonardi, R., Zhang, Y.M., Rock, C.O., et al.Coenzyme A: Back in actionProg. Lipid Res.44(2-3)125-153(2005) 2.Jackowski, S.Biosynthesis of pantothenic acid and coenzyme AEscherichia coli and Salmonella typhimurium: Cellular and molecular biology687-694(1996) 3.Begley, T.P., Kinsland, C., and Strauss, E.The biosynthesis of coenzyme A in bacteriaVitamins and Hormones61157-171(2001)

Cas No.	N/A	SDF
Sinónimos	CoA
Canonical SMILES	O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O)([O-])=O)([O-])=O)[C@H]1OP([O-])(O)=O.[Li+].[Li+].[Li+].OO[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O)([O-])=O)([O-])=O)[C@H]1OP([O-])(O)=O.[Li+].[Li+].[Li+].O
Formula	C21H33N7O16P3S.3Li [XH2O]	M.Wt	785.3
Solubility	PBS (pH 7.2): 10 mg/ml	Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	1.2734 mL	6.367 mL	12.734 mL
	5 mM	0.2547 mL	1.2734 mL	2.5468 mL
	10 mM	0.1273 mL	0.6367 mL	1.2734 mL

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 19 reference(s) in Google Scholar.)

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Coenzyme A (lithium salt hydrate) (Synonyms: CoA)

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