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IDT307

Catalog No.GC61837

IDT307, un anÁlogo del catiÓn orgÁnico MPP+, es un sustrato fluorescente especÍfico para DAT (sustrato fluorescente APP+).

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IDT307 Chemical Structure

Cas No.: 1141-41-9

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL DMSO)
49,50 $
Disponible
5 mg
45,00 $
Disponible
10 mg
72,00 $
Disponible
25 mg
135,00 $
Disponible
50 mg
225,00 $
Disponible
100 mg
360,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1].

IDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical (CSF-facing) membrane and sensitive to inhibition by the PMAT inhibitor quinine[1].IDT307 uptake and intracellular accumulation is greatly attenuated by ~70% in CP tissue from the Pmat knockout mouse[1].

References:
[1]. Tao Hu, et al. Molecular mechanisms of organic cation and anion transport at the blood‐CSF barrier. 01 April 2018.

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