Amifostine |
| Catalog No.GC15473 |
La amifostina (WR2721) es un agente citoprotector de amplio espectro y un radioprotector. La amifostina protege selectivamente los tejidos normales del daÑo causado por la radiaciÓn y la quimioterapia. La amifostina es un potente inductor del factor α1 inducible por hipoxia (HIF-α1) y p53. La amifostina protege las células del daÑo al eliminar los radicales libres derivados del oxÍgeno. La amifostina reduce la toxicidad renal y tiene acciÓn antiangiogénica.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 20537-88-6
Sample solution is provided at 25 µL, 10mM.
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Amifostine is a broad-spectrum cytoprotection agent against the DNA damaging effects of ionizing radiation and chemotherapy drug.
References:
[1]. Kouvaris, J.R., V.E. Kouloulias, and L.J. Vlahos, Amifostine: the first selective-target and broad-spectrum radioprotector. Oncologist, 2007. 12(6): p. 738-47.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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