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PKR-IN-2

Catalog No.GC33157

PKR-IN-2 es un activador de PKR de isoforma de piruvato quinasa extraÍdo de la patente WO2014139144A1, compuesto 160.

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PKR-IN-2 Chemical Structure

Cas No.: 1628428-01-2

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL DMSO)
354,00 $
Disponible
5mg
321,00 $
Disponible
10mg
459,00 $
Disponible
50mg
1.379,00 $
Disponible
100mg
1.930,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PKR-IN-2 is a pyruvate kinase (PKR) activator, extracted from patent WO2014139144A1, compound 160, has an IC50 of <100 nM for. PKR (R510Q), PKR (R532W), PKR (WT), and PKR (WT Cell Based).IC50 value: <100 nM (AC50)Target: PKR

[1]. Popovici-Muller, et al. Preparation of N-(piperidinecarbonylphenyl) sulfonamide compounds as pyruvate kinase modulators. From PCT Int. Appl. (2014), WO2014139144A1 20140918. [2]. Cianchetta Giovanni, et al. Preparation of aroylpiperidines, particularly arysulfonylamino and heteroarylsulfonylamino substituted, as pyruvate kinase PKM2 modulators useful in the treatment of cancer and compositions containing them. From PCT Int. Appl.

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