ARN19874 |
| Catalog No.GC42855 |
ARN19874 es un inhibidor de la actividad de la N-acilfosfatidiletanolamina fosfolipasa D (NAPE-PLD) selectivo, reversible y no competitivo con una IC50 de ~34 μM.
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Cas No.: 2190502-57-7
Sample solution is provided at 25 µL, 10mM.
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ARN19874 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD; IC50 = 33.7 µM). It is selective for NAPD-PLD over carbonic anhydrase II, neutral endopeptidase, and angiotensin-converting enzyme (ACE) up to 50 µM. ARN19874 (50 µM) increases the levels of certain NAPE substrates and decreases the endogenous levels of stearoyl ethanolamide , but not oleoyl ethanolamide or palmitoyl ethanolamide , in HEK293 cells.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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