- Cat.No. Nombre del producto Información
- GC13488 R8-T198wt Cell-permeable peptide inhibitor of Pim-1 kinase, derived from p27Kip1. Inhibits Pim-1 phosphorylation of p27Kip1 and Bad;
-
GP10075
PKA inhibitor fragment (6-22) amide
A synthetic peptide inhibitor of PKA
-
GP10119
Gap 27
A connexin-mimetic peptide
- GA24160 Rink amide AM resin (200-400 mesh, 0.5-1.2 mmol/g) Fmoc-Rink amide-AM resin, a standard resin for the Fmoc-SPPS of peptide amides.
- GA24159 RAD16-I Self-assembling amphiphilic peptide used as scaffold in tissue engineering and 3-dimensional cell culture.
- GA24158 Protein LMWP Low molecular weight protamine (LMWP) is a peptide fragment produced in our laboratory from enzymatic digestion of native protamine.
- GA24156 Prion Protein (106-126) (human) (scrambled) The 21-peptide NGAKALMGGHGATKVMVGAAA, a scrambled sequence of the human prion protein (106-126), is an important control in the study of the biological activity of prion protein peptides.
- GA24145 LL-37 (scrambled) Control peptide for LL37.
- GA24131 H-Lys-Phe-Glu-Arg-Gln-OH The peptide plays a widespread role in targeting proteins for enhanced degradation.
- GA24129 H-Leu-Gly-Leu-Leu-Leu-Arg-His-Leu-Arg-His-His-Ser-Asn-Leu-Leu-Ala-Asn-Ile-OH The peptide sequence B18, derived from the membrane-associated sea urchin sperm protein bindin, triggers fusion between lipid vesicles.
- GA24128 HIV-1 tat Protein (47-57) amide HIV-1 tat Protein (47-57) is a potent cell penetrating peptides.
- GA24119 H-Cys(Acm)-2-chlorotrityl resin (200-400 mesh, 0.4-0.7 mmol/g) H-Cys(Acm)-2-ClTrt resin is excellently suited for synthesizing peptides containing a C-terminal Cys(Acm).
- GA24112 Gluten Exorphin B5 Among all exogenous opioid peptides reported to date and especially among the gluten exorphins A, B and C, gluten exorphin B5 shows the most potent activity.
- GA24110 For-Met-Ala-Ser-OH fMAS was used as substrate in a continuous assay for peptide deformylase (PDF).
- GA24077 Catestatin (human) Catestatin, SSMKLSFRARAYGFRGPGPQL, a catecholamine release-inhibitory peptide corresponding to human chromogranin A (CHGA) 370-390.
- GA24061 Acetyl-(Phe¹)-Octreotide trifluoroacetate salt The peptide is an impurity of octreotide.
- GA24058 2-Chlorotrityl chloride resin (200-400 mesh, 1.5-1.9 mmol/g) A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc-strategy.
- GA24056 (β-Ala²?)-Glucagon trifluoroacetate salt The peptide is an impurity of glucagon.
- GA24053 (Trp?)-Octreotide acetate salt The peptide is an impurity of octreotide.
- GA24047 (Kyn²?)-Liraglutide trifluoroacetate salt The peptide is an impurity of Liraglutide.
- GA24043 (Des-Ser?)-Liraglutide trifluoroacetate salt The peptide is an impurity of Liraglutide.
- GA24041 (Des-His¹)-Glucagon trifluoroacetate salt The peptide is an impurity of glucagon.
- GA24040 (Des-Gly³¹)-Liraglutide trifluoroacetate salt The peptide is an impurity of Liraglutide.
- GA24039 (Des-Gly²?)-Liraglutide trifluoroacetate salt The peptide is an impurity of Liraglutide.
- GA24031 (D-Ala¹?)-Liraglutide trifluoroacetate salt The peptide is an impurity of Liraglutide.
- GA24029 (d(CH?)?¹,Tyr(Me)²,Dab?,Arg?)-Vasopressin The isosteric substitution of Asn5 by Dab in oxytocin, vasopressin and their analogs invariably leads to a dramatic loss of the biolical activities of the peptides.
- GA24025 (Aspartimide²¹)-Glucagon trifluoroacetate salt The peptide is an impurity of glucagon.
- GA24024 (Aspartimide¹?)-Glucagon trifluoroacetate salt The peptide is an impurity of glucagon.
- GA24020 (2-Hydroxy-Trp²?)-Liraglutide trifluoroacetate salt The peptide is an impurity of Liraglutide.
- GA24019 (2-(2-Trifluoromethyl-1,3-dithiolan-2-yl)-Trp²?)-Liraglutide trifluoroacetate salt The peptide is an impurity of Liraglutide.
- GA24018 (2-(1,3-Dithiolan-2-yl)-Trp²?)-Liraglutide trifluoroacetate salt The peptide is an impurity of Liraglutide.
- GC49743 Octapeptide-2 A thymosin β4-derived peptide
- GC49724 BIO-1211 (trifluoroacetate salt) A peptide inhibitor of α4β1 integrin
- GC49716 Cyclo(RGDyK) (trifluoroacetate salt) A cyclic peptide ligand of αVβ3 integrin
- GC49713 SIKVAV (acetate) A laminin α1-derived peptide
- GC49712 Acetyl Tetrapeptide-15 (acetate) A peptide derivative of endomorphin 2
- GC49711 Acetyl Dipeptide 1 cetyl ester (trifluoroacetate salt) A cosmeceutical peptide
- GC49705 Pentapeptide-18 (acetate) A peptide derivative of enkephalin
- GC49702 Papain Inhibitor (trifluoroacetate salt) A peptide inhibitor of papain
- GC49699 Acetyl Tetrapeptide-9 (acetate) A synthetic signal peptide
- GC49689 Pentapeptide-3 (acetate) A cosmeceutical peptide
- GC49685 Trifluoroacetyl Tripeptide-2 (acetate) A peptide inhibitor of pancreatic and neutrophil elastases
- GC49543 Hepcidin-25 (trifluoroacetate salt) A peptide hormone
- GC49493 IRL 1620 (trifluoroacetate salt) A peptide ETB receptor agonist
- GC49489 PBP 10 (trifluoroacetate salt) A peptide FPR2 antagonist
- GC49478 Decapeptide-12 (acetate) A tyrosinase inhibitor and cosmeceutical peptide
- GC49475 Triptorelin (trifluoroacetate salt) A synthetic GNRH peptide agonist
- GC49422 PAR2 (1-6) amide (human) (trifluoroacetate salt) A peptide agonist of PAR2
- GC49416 Gap 27 (trifluoroacetate salt) A connexin-mimetic peptide
- GC49338 Deltorphin II (trifluoroacetate salt) A peptide agonist of δ2-opioid receptors
- GC49332 Calcineurin Substrate (trifluoroacetate salt) A synthetic peptide substrate
- GC49302 Bactenecin (bovine) (trifluoroacetate salt) A cationic peptide
- GC49301 Nesiritide (acetate) A natriuretic peptide
- GC49266 Compstatin (trifluoroacetate salt) A peptide inhibitor of complement activation
- GC49264 Neuromedin U-23 (rat) (trifluoroacetate salt) A peptide NMUR agonist
- GC49263 Ac2-26 (human) (ammonium salt) An annexin A1-mimetic peptide
- GC49209 Antisauvagine-30 (trifluoroacetate salt) A peptide CRF2 antagonist
- GC49154 Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A synthetic peptide fragment of galanin and an agonist of the GAL2 receptor
- GC49143 Deslorelin (acetate) A peptide agonist of GnRH
- GC49123 Somatorelin (1-44) amide (human) (trifluoroacetate salt) A synthetic GHRH peptide
- GC49120 Prosaptide TX14(A) (trifluoroacetate salt) A peptide fragment of prosaposin and GPR37L1 and GPR37 agonist
- GC49099 Tuftsin (human) (trifluoroacetate salt) A phagocytosis-stimulating peptide
- GC49091 Hirudin (54-65; non-sulfated) (trifluoroacetate salt) A desulfated peptide fragment of hirudin
- GC49048 Guanylin (human) (trifluoroacetate salt) A peptide hormone activator of GC-C
- GC49014 Palmitoyl Tetrapeptide-7 (acetate) A cosmeceutical peptide
- GC48998 β-Defensin-1 (human) (trifluoroacetate salt) An antimicrobial peptide
- GC48997 Argipressin (acetate) A peptide hormone with vasoconstrictive and antidiuretic activities
- GC48989 LTX-315 (trifluoroacetate salt) A synthetic cationic amphiphilic peptide
- GC48985 NF-κB Inhibitor (trifluoroacetate salt) A cell-permeable peptide that blocks nuclear import of NF-κB
- GC48401 Risuteganib (trifluoroacetate salt) An anti-integrin peptide
- GC48399 MTP 131 (acetate) A mitochondria-targeted peptide antioxidant
- GC48358 Thymulin (acetate hydrate) A peptide hormone
- GC48348 Carbetocin (acetate) La carbetocina (acetato), un análogo de la oxitocina (OT), es un agonista del receptor de oxitocina con una Ki de 7,1 nM.
- GC48329 PKA Inhibitor (5-24) (trifluoroacetate salt) A synthetic peptide inhibitor of PKA
- GC48328 Obestatin (human) (trifluoroacetate salt) A peptide hormone
- GC48298 β-Defensin-2 (human) (trifluoroacetate salt) An antimicrobial peptide
- GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH (α-Melanocyte-Stimulating Hormone) TFA, un neuropéptido endÓgeno, es un agonista endÓgeno del receptor 4 de melanocortina (MC4R) con actividades antiinflamatorias y antipiréticas.
- GC48229 Urotensin II (goby) (trifluoroacetate salt) A peptide vasoconstrictor
- GC47966 PPACK (trifluoroacetate salt) An antithrombin peptide
- GC47530 Kocurin A peptide antibiotic
- GC47188 Dermorphin (acetate) An opioid peptide
- GC47097 CJC-1295 A synthetic peptide derivative of GHRH
- GC45750 Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) An actin-sequestering peptide
- GC45666 Palmitoyl Tripeptide-5 (trifluoroacetate salt) A cosmeceutical peptide
- GC45641 Acetyl Octapeptide-3 A cosmeceutical peptide
- GA23601 Teplow's Amyloid β-Protein (1-42) (scrambled II) This peptide is a specifically designed negative control in studies with Abeta42. It is "scrambled", which means it contains the same amino acids as Abeta42, but in different order. Referring to studies by Yamin and coworkers, Teplow's Amyloid β-Protein (1-42) does not show a number of phenomena regularly observed with Abeta42 (fibril formation, oligomerization, toxicity to neurons) and furthermore has a relatively flat hydropathy profile, which can be an advantage in several studies, for example in order to avoid unspecific interaction with the cell membrane.
- GA23600 Teplow's Amyloid β-Protein (1-40) (scrambled II) This peptide is a specifically designed negative control in studies with Abeta40. It is "scrambled", which means it contains the same amino acids as Abeta40, but in different order. Referring to studies by Yamin and coworkers, Teplow's Amyloid β-Protein (1-40) does not show a number of phenomena regularly observed with Abeta40 (fibril formation, oligomerization, toxicity to neurons) and furthermore has a relatively flat hydropathy profile, which can be an advantage in several studies, for example in order to avoid unspecific interaction with the cell membrane.
- GA23175 Mca-Amyloid β/A4 Protein Precursor₇₇₀ (667-676)-Lys(Dnp)-Arg-Arg amide This fluorescent (FRET) peptide substrate contains the wild-type amyloid precursor protein (APP) β-secretase cleavage site. Mca-SEVKMDAEFRK(Dnp)RR- amide has been used for assaying β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). The results suggested that TOP is a potential β-secretase candidate and is involved in the processing of APP in vivo. See also L-1905.
- GA21424 ent-Amyloid β-Protein (1-42) All-D Aβ (1-42) exhibits similar properites as the all-L Aβ. The peptide forms ion channels in lipid bilayers.
- GA21397 Dolastatin 15 La dolastatina 15 (DLS 15), un depsipéptido derivado de Dolabella auricularia, es un potente agente antimitÓtico estructuralmente relacionado con el agente antitubulina Dolastatina 10. La dolastatina 15 induce la detenciÓn del ciclo celular y la apoptosis en células de mieloma mÚltiple. La dolastatina 15 se puede utilizar como citotoxina ADC.
- GA20748 Amyloid β-Protein (3-42) The N-terminally truncated Aβ42 may be formed in increased amounts as AD progresses. Aβ 3-42 is the precursor of the Pyr-peptide. (Pyr³)-Aβ 3-42 positive plaques are resistant to age-dependent degradation likely due to their high stability and propensity to aggregate.
- GA20745 Amyloid β-Protein (25-35) amide The amidation of amyloid β-protein (25-35) leads to a product in which the amyloidogenic capacity of amyloid β-protein (25-35) has been strongly reduced, while the neurotoxic activity was found to be independent of the aggregated state of the peptide.
- GA20744 Amyloid β-Protein (2-42) Aβ 2-42 could be a biomarker for differentiating AD from other degenerative dementias, such as frontotemporal dementias (FTD). The peptide promotes phagocytosis by macrophages.
- GA20742 Amyloid β-Protein (17-40) Cleavage of APP by alpha- and gamma-secretase (i.e. the non-amyloidogenic pathway) yields p3 peptide, a mix of Aβ 17-40 and Aβ 17-42. p3 is a major constituent of diffuse plaques observed in AD brains and pre-amyloid plaques in people affected by Down syndrome.
- GA20738 Amyloid β-Protein (1-6) Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1-6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5-25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice.
- GA20722 Amyloid β-Protein (1-14) The N-terminal Aβ fragments Aβ1-14, Aβ1-15 (H-6368), and Aβ1-16 (H-2958) are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The presence of these small peptides is consistent with a catabolic amyloid precursor protein cleavage pathway by β- followed by α-secretase. It has been shown that Aβ1-14, Aβ1-15, and Aβ1-16 increase dose-dependently in response to γ-secretase inhibitor treatment while Aβ1-42 levels are unchanged.
- GA20718 Amyloid β/A4 Protein Precursor₇₇₀ (667-676) The peptide substrate APP (667-676), SEVKMDAEFR, corresponds to the wild-type amyloid precursor protein (APP) β-secretase cleavage site. SEVKMDAEFR has been used for assaying β-secretase activity.
- GA20572 Ac-Gly-Lys-OMe Substrate for the determination of urokinase activity. It is also cleaved by thrombin, plasmin and trypsin as well as complement component C3/C5 convertases. Also known as GK-peptide, used in studies on protein glycation and formation of Maillard products.
- GA20534 Acetyl-Amyloid β-Protein (15-20) amide Incubation of Ac-QKLVFF-NH? with the amyloid β-protein (1-40) inhibited polymerization of the amyloid β-protein (1-40) into amyloid fibrils. The peptide is thought to block the polymerization sites.
- GA20283 (Pyr³)-Amyloid β-Protein (3-40) The pyroglutamate-modified amyloid-β peptides derived from Aβ40 (H-7422) and Aβ42 (H-4796) have gained considerable attention as potential key participants in the pathology of Alzheimer's disease (AD) due to their abundance in AD brain, high aggregation propensity, stability, and cellular toxicity. Aβ40 and 42 can be N-terminally truncated by action of cathepsin B. The cyclization of Glu³ is catalyzed by glutaminyl cyclase. Hence, inhibition of these enzymes could be a therapeutic approach to AD.