- Cat.No. Nombre del producto Información
- GC43239 Chk2 Inhibitor El inhibidor de Chk2 (compuesto 1) es un inhibidor potente y selectivo de la quinasa de punto de control 2 (Chk2), con IC50 de 13,5 nM y 220,4 nM para Chk2 y Chk1, respectivamente. El inhibidor de Chk2 puede provocar un fuerte efecto de radioprotecciÓn mediado por Chk2 dependiente de ataxia telangiectasia mutada (ATM).
- GC49664 CB-1158 An arginase inhibitor
- GC48548 iBET-BD2 A BD2 bromodomain inhibitor
- GC48493 PCI 45227 PCI 45227 (PCI-45227) es un metabolito dihidrodiolactivo de ibrutinib, tiene una actividad inhibitoria hacia BTK aproximadamente 15 veces menor que la de ibrutinib.
- GC48427 CAY10774 A PD-1/PD-L1 interaction inhibitor
- GC47741 Nalanthalide A fungal metabolite with potassium channel inhibitory and antiviral activities
- GC47533 L-778,123 A dual inhibitor of FTase and GGTase I
- GC47387 G6PDi-1 G6PDi-1 es un inhibidor reversible y no competitivo de glucosa-6-fosfato deshidrogenasa (G6PD) con una IC50 de 0,07 μM.
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC46549 2F-Peracetyl-Fucose 2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) actÚa como un potente inhibidor de fucosiltransferasa (FUT).
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GC18572
Concanavalin A
La concanamicina A pertenece a las concanamicinas, una familia de antibióticos macrólidos aislados de Streptomyces diastatochromogenes que son inhibidores altamente activos y selectivos de la vacuolar proton-ATPasa (v-[H+] ATPasa).
- GC46226 SS-208 SS-208 es un inhibidor selectivo de HDAC6, con una IC50 de 12 nM. SS-208 posee actividad antitumoral en melanoma.
- GC45966 LH1307 A PD-1/PD-L1 interaction inhibitor
- GC45771 LH1306 A PD-1/PD-L1 interaction inhibitor
- GC45515 MX1013 MX1013 es un inhibidor dipéptido caspasa potente e irreversible con actividad antiapoptÓtica. MX1013 inhibe la caspasa 3 humana recombinante con una IC50de 30 nM.
- GC44919 SP 600125, negative control SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM.
- GC44505 Oleyl Anilide AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.
- GC43928 JJH260 JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.
- GC43307 Concanamycin B Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM).
- GC42668 ABC34 ABC34 is an inactive control probe for JJH260, the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).
- GC42112 2-Acetyl-5-tetrahydroxybutyl Imidazole Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine.
- GC18716 Bisindolylmaleimide XI (hydrochloride) Bisindolylmaleimide XI (clorhidrato) (Ro 32-0432) es un inhibidor de PKC potente, selectivo y activo por vía oral con IC50 de 9 nM, 28 nM, 31 nM, 37 nM y 108 nM para PKCα, PKCβI, PKCβII, PKCγ y PKCε , respectivamente.
- GC18443 Acetyl-6-formylpterin Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation.