- Cat.No. Nombre del producto Información
- GP10126 Diazepam-Binding Inhibitor Fragment, human Diazepam-Binding Inhibitor (DBI) Fragment is encoded by the DBI gene in human.
- GC44775 PTP1B Inhibitor PTP1B Inhibitor es un inhibidor alostérico no competitivo de la proteÍna tirosina fosfatasa PTP1B, con un IC50 de 8 μM.
- GC40105 βARK1 Inhibitor βInhibidor de ARK1 (5-[2-(5-nitro-2-furil)vinil]-2-furoato de metilo) es un inhibidor de GRK2 (β-ARK1).
- GC52476 Bax Inhibitor Peptide V5 (trifluoroacetate salt) A Bax inhibitor
- GC49646 Aurothioglucose (hydrate) A TrxR inhibitor
- GC49637 O-desethyl Dapagliflozin An SGLT2 inhibitor and active metabolite of dapagliflozin
- GC45911 Zopolrestat Zopolrestat (CP73850) es un potente inhibidor de la aldosa reductasa (AR) activo por vÍa oral con una IC50 de 3,1 nM.
- GC45618 (±)-trans-GK563 A GVIA iPLA2 inhibitor
- GC45252 (-)-Sitagliptin Carbamoyl Glucuronide (-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
- GC45164 WWL229 WWL229 es un inhibidor selectivo de la carboxilesterasa 3 (Ces3) con una IC50 de 1,94 μM.
- GC45144 Vildagliptin carboxylic acid metabolite (trifluoroacetate salt) Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans.
- GC44895 Sitagliptin N-Sulfate (sodium salt) Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
- GC44529 P053 P053 es un inhibidor potente, no competitivo y selectivo de la ceramida sintasa 1 (CerS1) con una IC50 de 0,5μM.
- GC44516 Orlistat Degradation Product (sodium salt) Orlistat degradation product is a degradation product of the digestive lipase inhibitor orlistat.
- GC44481 O-7460 O-7460 es un inhibidor de DAGLα potente y selectivo, con una IC50 de 0,69 μM.
- GC44341 ND-336 ND-336 es un inhibidor selectivo de la metaloproteinasa de matriz (MMP)-2, MMP-9 y MMP-14, con Kis de 85, 150 y 120 nM, respectivamente.
- GC44226 MLS-0322825 Cmpd 23 MLS-0322825 Cmpd 23 es un inhibidor selectivo de la proteÍna tirosina fosfatasa de bajo peso molecular (LMPTP), con una IC50 de 0,8 μM LMPTP-A.
- GC44225 ML-345 ML-345 es un potente y selectivo inhibidor de molécula pequeña de la enzima degradadora de insulina (IDE), con un valor IC50 de 188 nM.
- GC44221 ML-262 ML-262 is an inhibitor of hepatic lipid droplet formation (IC50 = 6.4 nM in murine AML-12 cells), which is associated with non-alcoholic fatty liver disease.
- GC43803 HA-1077 (hydrochloride) Fasudil (HA-1077; AT877) dihidrocloruro es un inhibidor rhoa/roca inespecÍfico y también tiene un efecto inhibitorio en las proteÍnas quinasas, con un KI de 0.33 ⋼ m para el rock111&&&&&&77TRESTO. offlineefficient_models_2022q2.md;M, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively.en_es_2021q4.mdHA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator.en_es_2021q4.md
- GC43773 Glyburide (potassium salt) Glyburide is a sulfonylurea and an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.3 nM).
- GC41873 10-Thiastearic Acid Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools.
- GC40666 Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (DDC) inhibits heme production by inhibiting ferrochelatase, the enzyme that catalyzes the addition of Fe2+ to protoporphyrin IX to create heme B.
- GC40190 Febuxostat Acyl Glucuronide Febuxostat acyl glucuronide is a metabolite of the xanthine oxidoreductase inhibitor febuxostat.
- GC18762 Remogliflozin A La remogliflozina A es un inhibidor potente y selectivo de SGLT2 (cotransportador de sodio-glucosa 2) con Kis de 12,4 y 26 nM para SGLT2 humano y de rata, respectivamente.
- GC18718 bpV(pic) (potassium hydrate) bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM).
- GC18693 Fascaplysin (chloride) La fascaplysin (cloruro) es un pigmento rojo antimicrobiano y citotÓxico, que puede provenir de la esponja marina (Fascaplysin (cloruro)opsis sp.