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Cefuroxime axetil

Catalog No.GC39548 Copy One-Click Copy Product Info

Cefuroxime Axetil, un profÁrmaco de la cefalosporina cefuroxima y un antibiÓtico de amplio espectro, inhibe varios organismos grampositivos y gramnegativos, incluidos los que se asocian con mayor frecuencia con diversas infecciones comunes adquiridas en la comunidad.

Products are for research use only. Not for human use. We do not sell to patients.

Cefuroxime axetil Chemical Structure

Cas No.: 64544-07-6

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL DMSO)
20,00 $
Disponible
5mg
18,00 $
Disponible
10mg
27,00 $
Disponible
25mg
48,00 $
Disponible
50mg
72,00 $
Disponible
100mg
109,00 $
Disponible

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Cefuroxime axetil

Cefuroxime Axetil, a prodrug of the cephalosporin cefuroxime and an oarl broad spectrum antibiotic, inhibits several gram-positive and gram-negative organisms, including those most frequently associated with various common community-acquired infections[1].

[1]. Scott LJ, et al. Cefuroxime axetil: an updated review of its use in the management of bacterial infections. Drugs. 2001;61(10):1455-500.

Chemical Properties of Cefuroxime axetil

Cas No. 64544-07-6 SDF
Canonical SMILES O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)OC(OC(C)=O)C
Formula C20H22N4O10S M.Wt 510.47
Solubility DMSO: 250 mg/mL (489.74 mM) Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Cefuroxime axetil

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.959 mL 9.7949 mL 19.5898 mL
5 mM 391.8 μL 1.959 mL 3.918 mL
10 mM 195.9 μL 979.5 μL 1.959 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Cefuroxime axetil

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Cefuroxime axetil

Average Rating: 5 ★★★★★ (Based on Reviews and 28 reference(s) in Google Scholar.)

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