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Cyclic di-GMP

Catalog No.GC15048

El di-GMP cíclico es un agonista de STING y un segundo mensajero bacteriano que coordina diferentes aspectos del crecimiento y el comportamiento bacteriano, incluida la motilidad, la virulencia, la formación de biopelículas y la progresión del ciclo celular. El di-GMP cíclico tiene actividad de proliferación de células anticancerígenas y también induce una expresión elevada del receptor CD4 y la detención del ciclo celular. El di-GMP cíclico se puede utilizar en la investigación del cáncer.

Products are for research use only. Not for human use. We do not sell to patients.

Cyclic di-GMP Chemical Structure

Cas No.: 61093-23-0

Tamaño Precio Disponibilidad Cantidad
1mg
320,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Cyclic-di-GMP is a STING agonist and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.

References:
[1]. Nakamura T, et al. Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma. J Control Release. 2015 Oct 28;216:149-57.
[2]. Burdette DL, et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8.

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