Cyclic di-GMP |
| Catalog No.GC15048 |
Cyclic di-GMP는 STING 작용제이자 운동성, 독성, 생물막 형성 및 세포 주기 진행을 비롯한 세균 성장 \u200b\u200b및 행동의 다양한 측면을 조정하는 세균 2차 전달자입니다. Cyclic di-GMP는 항암 세포 증식 활성을 가지며 CD4 수용체 발현 증가 및 세포 주기 정지를 유도합니다. 순환 di-GMP는 암 연구에 사용할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 61093-23-0
Sample solution is provided at 25 µL, 10mM.
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Cyclic-di-GMP is a STING agonist and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.
References:
[1]. Nakamura T, et al. Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma. J Control Release. 2015 Oct 28;216:149-57.
[2]. Burdette DL, et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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