Diquat (bromide) |
Catalog No.GC47238 |
El diquat (bromuro) es un herbicida integral comÚnmente utilizado en el cultivo de algodÓn, soja y otros cultivos para combatir las malas hierbas no deseadas.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 85-00-7
Sample solution is provided at 25 µL, 10mM.
Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).1 Diquat administration has been used to induce oxidative stress in vitro and in animal models.2,3,4 It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.2 Formulations containing diquat have been used in agriculture for crop desiccation and defoliation.
1.Moreland, D.E.Mechanisms of action of herbicidesAnn. Rev. Plant Physiol.31597-638(1980) 2.Cao, S., Wu, H., Wang, C., et al.Diquat-induced oxidative stress increases intestinal permeability, impairs mitochondrial function, and triggers mitophagy in pigletsJ. Anim. Sci.96(5)1795-1805(2018) 3.Singh, P., Hanson, P.S., and Morris, C.M.Sirtuin-2 protects neural cells from oxidative stress and is elevated in neurodegenerationParkinsons Dis.2017:2643587(2017) 4.TomÁšek, O., GabrielovÁ, B., Ka?er, P., et al.Opposing effects of oxidative challenge and carotenoids on antioxidant status and condition-dependent sexual signallingSci. Rep.6:23546(2016)
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(Based on Reviews and 26 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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