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DMNB-caged-Serine

Catalog No.GC50420 Copy One-Click Copy Product Info

La serina enjaulada con DMNB es un aminoÁcido fotoenjaulado.

Products are for research use only. Not for human use. We do not sell to patients.

DMNB-caged-Serine Chemical Structure

Cas No.: 780009-55-4

Tamaño Precio Disponibilidad Cantidad
50mg
246,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of DMNB-caged-Serine

DMNB-caged serine. Photoactivated to release serine by visible blue light (405 nm) in cells. Incorporated into S.cerevisiae proteins when introduced into growth medium at millimolar concentrations.

Lemke et al (2007) Control of protein phosphorylation with a genetically encoded photocaged amino acid. Nat.Chem.Biol. 3 769 PMID:17965709

Chemical Properties of DMNB-caged-Serine

Cas No. 780009-55-4 SDF
Canonical SMILES COC1=CC(COC[C@@H](C(O)=O)N)=C([N+]([O-])=O)C=C1OC
Formula C12H16N2O7 M.Wt 300.26
Solubility DMSO : 250 mg/mL (832.61 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of DMNB-caged-Serine

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.3304 mL 16.6522 mL 33.3045 mL
5 mM 666.1 μL 3.3304 mL 6.6609 mL
10 mM 333 μL 1.6652 mL 3.3304 mL
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In vivo Formulation Calculator (Clear solution) of DMNB-caged-Serine

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for DMNB-caged-Serine

Average Rating: 5 ★★★★★ (Based on Reviews and 36 reference(s) in Google Scholar.)

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