Ac-Lys-OH |
Catalog No.GA20612
One-Click Copy Product Info
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Ac-Lys-OH es un metabolito endÓgeno.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1946-82-3
Sample solution is provided at 25 µL, 10mM.
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Ac-Lys-OH is an important acetylated amino acid derivative, which is often used to increase the ligation/cyclization ratio in the reaction for generating peptide nitriles [1]. Ac-Lys-OH can be used in the amine titration experiment to confirm the presence of the active formyl group on the immobilized pyridoxal phosphate (PLP)[2]. Ac-Lys-OH has been widely used as a model molecule to study the steady-state kinetic parameters of the carboxylate oxygen exchange reaction[3].
References:
[1] Thoma B, Powner M W. Selective synthesis of lysine peptides and the prebiotically plausible synthesis of catalytically active diaminopropionic acid peptide nitriles in water[J]. Journal of the American Chemical Society, 2023, 145(5): 3121-3130.
[2] Lee K H, Distefano M D, Seelig B. Facile immobilization of pyridoxal 5′-phosphate using p-diazobenzoyl-derivatized Sepharose 4B[J]. Results in chemistry, 2023, 6: 101044.
[3] Hajkova D, Rao K C S, Miyagi M. pH dependency of the carboxyl oxygen exchange reaction catalyzed by lysyl endopeptidase and trypsin[J]. Journal of proteome research, 2006, 5(7): 1667-1673.
| Cas No. | 1946-82-3 | SDF | |
| Formula | C8H16N2O3 | M.Wt | 188.23 |
| Solubility | H2O : ≥ 100 mg/mL (531.29 mM); DMSO : 25 mg/mL (132.82 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C) | Storage | Store at RT,protect from light |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 5.3126 mL | 26.5632 mL | 53.1265 mL |
| 5 mM | 1.0625 mL | 5.3126 mL | 10.6253 mL |
| 10 mM | 531.3 μL | 2.6563 mL | 5.3126 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)