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Cucurbitacin IIa

Catalog No.GC35758

La cucurbitacina IIa es un triterpeno aislado de Hemsleya amalils Diels, induce la apoptosis de las células cancerosas, reduce la expresiÓn de survivina, reduce la fosfohistona H3 y aumenta la PARP escindida en las células cancerosas.

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Cucurbitacin IIa Chemical Structure

Cas No.: 58546-34-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells[1].

[1]. Boykin C, et al. Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation. Br J Cancer. 2011 Mar 1;104(5):781-9.

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