HPV16-E711-20 epitope |
| Catalog No.GC36256 |
El epÍtopo HPV16-E711-20 es un conocido epÍtopo de linfocito T citotÓxico (CTL) humano restringido por HLA-A*0201 de la proteÍna HPV16 E7 que muestra una uniÓn de alta afinidad a HLA-A2 in vitro. Los epÍtopos de CTL de HPV16 pueden ser buenos candidatos para el desarrollo de una vacuna antitumoral eficaz basada en péptidos.
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Cas No.: 160040-04-0
Sample solution is provided at 25 µL, 10mM.
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HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. HPV16 CTL epitopes may be good candidates for the development of an effective peptide-based antitumor vaccine[1].
[1]. Ding Z, et al. Cytolytic activity of the human papillomavirus type 16 E711-20 epitope-specific cytotoxic T lymphocyte is enhanced by heat shock protein 110 in HLA-A*0201 transgenic mice. Clin Vaccine Immunol. 2013 Jul;20(7):1027-33.
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