HPV16-E711-20 epitope |
| Katalog-Nr.GC36256 |
Das HPV16-E711-20-Epitop ist ein bekanntes HLA-A*0201-restringiertes humanes zytotoxisches T-Lymphozyten(CTL)-Epitop des HPV16-E7-Proteins, das in vitro eine hochaffine Bindung an HLA-A2 zeigt. HPV16-CTL-Epitope kÖnnten gute Kandidaten fÜr die Entwicklung eines wirksamen Antitumor-Impfstoffs auf Peptidbasis sein.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 160040-04-0
Sample solution is provided at 25 µL, 10mM.
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HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. HPV16 CTL epitopes may be good candidates for the development of an effective peptide-based antitumor vaccine[1].
[1]. Ding Z, et al. Cytolytic activity of the human papillomavirus type 16 E711-20 epitope-specific cytotoxic T lymphocyte is enhanced by heat shock protein 110 in HLA-A*0201 transgenic mice. Clin Vaccine Immunol. 2013 Jul;20(7):1027-33.
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