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PrPSc-IN-1

Catalog No.GC37019

PrPSc-IN-1 es una sonda fluorescente, se une a la proteÍna PrPSc mal plegada, inhibe su acumulaciÓn, con una IC50 de 1,6 μM.

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PrPSc-IN-1 Chemical Structure

Cas No.: 1315475-30-9

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1]. IC50:1.6 μM (PrPSc)[1]

[1]. Zaccagnini L, et al. Identification of novel fluorescent probes preventing PrPSc replication in prion diseases. Eur J Med Chem. 2017 Feb 15;127:859-873.

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