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Chloromethyl Methyl Carbonate (Synonyms: Tenofovir Impurity 66)

Catalog No.GD08092 Copy One-Click Copy Product Info

Chloromethyl methyl carbonate (Tenofovir Impurity 66) is adrug intermediatefor synthesis of various active compounds.

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Chloromethyl Methyl Carbonate Chemical Structure

Cas No.: 40510-81-4

Tamaño Precio Disponibilidad Cantidad
5g
13,00 $
Disponible
10g
18,00 $
Disponible
25g
33,00 $
Disponible
50g
51,00 $
Disponible
100g
79,00 $
Disponible
500g
197,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of Chloromethyl Methyl Carbonate

Chloromethyl methyl carbonate (Tenofovir Impurity 66) is adrug intermediatefor synthesis of various active compounds.

Chemical Properties of Chloromethyl Methyl Carbonate

Cas No. 40510-81-4 SDF
Sinónimos Tenofovir Impurity 66
Formula C3H5ClO3 M.Wt 124.52
Solubility Storage 4°C, sealed storage, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Chloromethyl Methyl Carbonate

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 8.0308 mL 40.1542 mL 80.3084 mL
5 mM 1.6062 mL 8.0308 mL 16.0617 mL
10 mM 803.1 μL 4.0154 mL 8.0308 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Chloromethyl Methyl Carbonate

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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