Glycohyocholic Acid (Synonyms: Glycine Hyocholate) |
| Catalog No.GC40912 |
El Ácido glicohiocÓlico (GHCA) es una forma conjugada con glicina del Ácido hiocÓlico del Ácido biliar primario.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 32747-08-3
Sample solution is provided at 25 µL, 10mM.
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Glycohyocholic acid (GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid .[1] GHCA is upregulated 6.6-fold in the serum of patients with cirrhosis induced by hepatitis C virus (HCV) compared to healthy controls.[2] Plasma levels of GHCA increase in patients who are no longer diabetic following gastric bypass surgery.[3]
Reference:
[1]. Guo, L., Milburn, M.V., Ryals, J.A., et al. Plasma metabolomic profiles enhance precision medicine for volunteers of normal health. Proc. Nat. Acad. Sci. USA 112(35), E4901-E4910 (2015).
[2]. Fitian, A.I., Nelson, D.R., Liu, C., et al. Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MS. Liver Int. 34(9), 1428-1444 (2014).
[3]. Yu, H., Ni, Y., Bao, Y., et al. Chenodeoxycholic acid as a potential prognostic marker for roux-en-Y gastric bypass in chinese obese patients. J. Clin. Endocrinol. Metab. 100(11), 4222-4230 (2015).
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