Imipenem (hydrate) (Synonyms: NFormimidoyl Thienamycin) |
| Catalog No.GC43898 |
Imipenem (hidrato), un derivado cristalino estable de la tienamicina, es un antibiÓtico y tiene una excelente actividad contra una amplia gama de bacterias aerobias y anaerobias grampositivas y gramnegativas.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 74431-23-5
Sample solution is provided at 25 µL, 10mM.
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Imipenem monohydrate, a member of the carbapenem class of antibiotics isolated from the soil organism Streptomyces cattleya[1], is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including several multi-drug resistant bacterial species. Imipenem acts as cell wall-targeting antibiotic[2][3].
References:
[1]. Zhanel GG, et al. Imipenem and meropenem: Comparison of in vitro activity, pharmacokinetics, clinical trials and adverse effects. Can J Infect Dis. 1998 Jul;9(4):215-28.
[2]. Jacoby GA, et al. AmpC beta-lactamases. Clin Microbiol Rev. 2009 Jan;22(1):161-82.
[3]. Balibar CJ, et al. cwrA, a gene that specifically responds to cell wall damage in Staphylococcus aureus. Microbiology. 2010 May;156(Pt 5):1372-83.
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