Iperoxo (iodide) |
| Catalog No.GC43906 |
El iperoxo (yoduro) es un potente superagonista del receptor muscarÍnico de acetilcolina (mAChR).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 247079-84-1
Sample solution is provided at 25 µL, 10mM.
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Iperoxo is an agonist of muscarinic acetylcholine receptors. It stimulates [35S]GTPγS binding to CHO cell membranes expressing human M2 muscarinic receptors and cell membranes expressing M4 muscarinic receptors (EC50s = 2.12 and 8.47 nM, respectively). Iperoxo induces M1-dependent inhibition of the twitch response in electrically-stimulated isolated rabbit vas deferens (pD2 = 9.87) and M3-mediated contraction of isolated guinea pig ileum (pD2 = 9.78). In vivo, iperoxo reduces formalin-induced paw licking and acetic acid-induced writhing in mice (ED50s = 0.004 and 0.001 mg/kg, respectively).
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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