MC-GGFG-DX8951 (Synonyms: MC-GGFG-DX8951) |
| Catalog No.GC39309 |
MC-GGFG-DX8951 (MC-GGFG-DX8951) es un conjugado de enlace de fÁrmaco para ADC. MC-GGFG-DX8951 es un derivado de DX8951 (un inhibidor de la ADN topoisomerasa I) con un conector MC-GGFG escindible por proteasa. MC-GGFG-DX8951 muestra actividad antitumoral y se puede utilizar para preparar el conjugado de anticuerpos DX8951 (ADC).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1600418-29-8
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker[1].
[1]. Nakada T, et al. Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1542-1545.
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *