JZP 361 |
| Catalog No.GC50284 |
JZP 361 es un inhibidor potente, reversible y selectivo de la MAGL recombinante humana (hMAGL) con una IC50 de 46 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1680193-80-9
Sample solution is provided at 25 µL, 10mM.
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Potent and selective reversible MAGL inhibitor (IC50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC50 values are 1.79 and 7.24 μM, respectively). Displays affinity for H1 receptors (pA2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μM.
Patel et al (2015) Loratadine analogues as MAGL inhibitors. Bioorg.Med.Chem.Lett. 25 1436 PMID:25752982
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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