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L-Guanosine

Catalog No.GC66622 Copy One-Click Copy Product Info

L-guanosina es la configuración L de la guanosina. La guanosina es un nucleósido de purina con actividad anti-herpesvirus.

Products are for research use only. Not for human use. We do not sell to patients.

L-Guanosine Chemical Structure

Cas No.: 26578-09-6

Tamaño Precio Disponibilidad Cantidad
100mg
133,00 $
Disponible
250mg
212,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of L-Guanosine

L-Guanosine is the L-configuration of Guanosine . Guanosine is a purine nucleoside with anti-herpesvirus activity[1][2].

[1]. Du Y, et al. Chirality from D-guanosine to L-guanosine shapes a stable gel for three-dimensional cell culture. Chem Commun (Camb). 2021 Dec 3;57(96):12936-12939.
[2]. De Clercq E. Guanosine analogues as anti-herpesvirus agents. Nucleosides Nucleotides Nucleic Acids. 2000 Oct-Dec;19(10-12):1531-41.

Chemical Properties of L-Guanosine

Cas No. 26578-09-6 SDF
Formula C10H13N5O5 M.Wt 283.24
Solubility DMSO : 100 mg/mL (353.06 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of L-Guanosine

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.5306 mL 17.6529 mL 35.3057 mL
5 mM 706.1 μL 3.5306 mL 7.0611 mL
10 mM 353.1 μL 1.7653 mL 3.5306 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of L-Guanosine

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for L-Guanosine

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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