LM985 |
| Catalog No.GC33409 |
LM985 es uno de una serie de compuestos basados en la estructura del anillo de flavona, con actividades antitumorales.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 87626-56-0
Sample solution is provided at 25 µL, 10mM.
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LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities.
LM985 shows inhibitory effects against MAC 13 cells, but MAC 15A cells are less sensitive to LM985[1].
LM985 (200 mg/kg, s.c.) shows moderate activity against MAC 13, and after repeated injection 7 days, responses are considerably enhanced[2].
[1]. M. C. Bibby, et al. Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer. 1987 Feb; 55(2): 159-163. [2]. J. A. Double, et al. Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer. 1986 Oct; 54(4): 595-600.
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