LM985 |
Catalog No.GC33409 |
LM985 fait partie d'une série de composés basés sur la structure cyclique des flavones, avec des activités anti-tumorales.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 87626-56-0
Sample solution is provided at 25 µL, 10mM.
LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities.
LM985 shows inhibitory effects against MAC 13 cells, but MAC 15A cells are less sensitive to LM985[1].
LM985 (200 mg/kg, s.c.) shows moderate activity against MAC 13, and after repeated injection 7 days, responses are considerably enhanced[2].
[1]. M. C. Bibby, et al. Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer. 1987 Feb; 55(2): 159-163. [2]. J. A. Double, et al. Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer. 1986 Oct; 54(4): 595-600.
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