LY2794193 |
| Catalog No.GC31066 |
LY2794193 es un agonista del receptor mGlu3 muy potente y selectivo (hmGlu3 Ki = 0,927 nM, EC50 = 0,47 nM; hmGlu2 Ki = 412 nM, EC50 = 47,5 nM).
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Cas No.: 2173037-97-1
Sample solution is provided at 25 µL, 10mM.
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LY2794193 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM,EC50=0.47 nM; hmGlu2 Ki=412 nM,EC50=47.5 nM)[1].
[1]. Monn JA, et al. Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3 Receptor Agonist. J Med Chem. 2018 Mar 22;61(6):2303-2328.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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