MK-0941 |
| Catalog No.GC44210 |
MK-0941 es un potente activador de glucoquinasa alostérico activo por vÍa oral, con CE50 de 240 y 65 nM para glucoquinasa humana recombinante en presencia de glucosa 2,5 y 10 mM, respectivamente.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1137916-97-2
Sample solution is provided at 25 µL, 10mM.
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MK-0941 is a glucokinase activator with EC50 values of 0.24 and 0.065 µM at low (2.5 mM) and high (10 mM) concentrations of glucose, respectively. It increases insulin secretion from isolated rat islets of Langerhans and glucose uptake by hepatocytes in vitro. MK-0941 reduces blood glucose levels in high-fat diet-fed db/db mice and in high-fat diet-fed mice with diabetes induced by streptozotocin .
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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