ML303 |
| Catalog No.GC65122 |
ML303 es un antagonista de la proteÍna no estructural 1 (NS1) del virus de la influenza de pirazolopiridina (IC90 = 155 nM), con un EC50 de 0,7 μM para el virus de la influenza A H1N1.
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Cas No.: 1638211-04-7
Sample solution is provided at 25 µL, 10mM.
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ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1[1].
ML303 (20 μM, 6 h) treatment restore IFN-β mRNA levels in MDCK cells[1].
[1]. Patnaik S, et al. Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists. Bioorg Med Chem Lett. 2019 May 1;29(9):1113-1119.
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