N3-PEG3-CH2CH2-Boc |
Catalog No.GC65822 |
N3-PEG3-CH2CH2-Boc es un enlazador PEG ADC de 3 unidades escindible que se utiliza en la sÍntesis de conjugados de anticuerpo-fÁrmaco (ADC). N3-PEG3-CH2CH2-Boc también es un enlazador PROTAC basado en PEG y alquilo/éter que se puede utilizar en la sÍntesis de PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 252881-73-5
Sample solution is provided at 25 µL, 10mM.
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *