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NBC 6

Catalog No.GC50611

NBC 6 es un potente inhibidor selectivo del inflamasoma NLRP3 (IC50= 574 nM) que actÚa independientemente de Ca2+.

Products are for research use only. Not for human use. We do not sell to patients.

NBC 6 Chemical Structure

Cas No.: 2068818-02-8

Tamaño Precio Disponibilidad Cantidad
10 mg
288,00 $
Disponible
50 mg
1.199,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

NLRP3 inflammasome inhibitor (IC50 = 574 nM). Inhibits nigericin-induced inflammasome activation in THP-1 cells and Imiquimod induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs).

Baldwin et al (2017) Boron-based inhibitors of the NLRP3 inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355

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Review for NBC 6

Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

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