NH2-PEG3-C1-Boc (Synonyms: PROTAC Linker 5) |
| Catalog No.GC61853 |
NH2-PEG3-C1-Boc (PROTAC Linker 5) es un enlazador PROTAC basado en PEG que se puede utilizar en la sÍntesis de PROTAC.
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Cas No.: 189808-70-6
Sample solution is provided at 25 µL, 10mM.
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NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References:
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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