Paraherquamide A (Synonyms: (–)-Paraherquamide, VM 29919) |
| Catalog No.GC44563 |
La paraherquamida A (PNU-97333) es un metabolito tÓxico que se puede aislar de Penicillium paraherquei.
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Cas No.: 77392-58-6
Sample solution is provided at 25 µL, 10mM.
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Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 µg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg).
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