Pifusertib hydrochloride (Synonyms: TAS-117 hydrochloride) |
Catalog No.GC69991 |
Pifusertib (TAS-117) hidrocloruro es un inhibidor de Akt isómero efectivo, selectivo y con actividad oral (con IC50 de 4.8, 1.6 y 44 nM para Akt1, 2 y 3 respectivamente). Pifusertib hidrocloruro estimula la actividad anti-mieloma y mejora el estrés del retículo endoplásmico inducido por la inhibición proteasómica letal. Pifusertib hidrocloruro induce apoptosis y autofagia celular.
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Cas No.: 2930090-28-9
Sample solution is provided at 25 µL, 10mM.
Average Rating: 5
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