PK14105 |
| Catalog No.GC30398 |
PK14105 es una evaluaciÓn biolÓgica como radioligando potencial para estudios PET de receptores PBBS.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 107257-28-3
Sample solution is provided at 25 µL, 10mM.
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PK14105 is a biological evaluation as a potential radioligand for PET studies of PBBS receptors.in vivo binding experiments, in which PK 14105 was injected into rats with unilaterallylesioned striata, demonstrate that PK 14105 rapidly crosses the blood-brain-barrier and that thereis a marked retention of radioactivity in the lesioned striatum not seen in the unlesioned striatum or cerebellar vermis[1]It can also inhibit receptor ligands, calcium channel ligands and co-transporter in all salivary glands. [2]
[1]. Pascali C et al. The radiosynthesis of [18F]PK 14105 as an alternative radioligand for peripheral type benzodiazepine binding sites. Int J Rad Appl Instrum A. 1990;41(5):477-82. [2]. Franklin C. Wong et al. Affinity Labeling of Membrane Receptors Using Tissue-Penetrating Radiations. Biomed Res Int. 2013, 503095.
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