GPCR/G protein
Research Areas
- Neuropeptide FF/AF Receptors(54)
- Neuropeptide S Receptor(3)
- GPBA Receptor(5)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- Formyl Peptide Receptors(11)
- 5-HT Receptor(431)
- Acetylcholine(28)
- Adenosine Deaminase(10)
- Adenosine Receptor(143)
- Adenosine Kinase(5)
- Adiponectin Receptor(3)
- Adrenergic Receptor(450)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(118)
- Bombesin Receptors(26)
- Bradykinin Receptors(30)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(121)
- Calcimimetic Agent(2)
- CaSR(28)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(98)
- Chemokine Receptors(23)
- CRF1 Receptors(10)
- CRF2 Receptors(3)
- CXCR(108)
- CysLT1 receptor(1)
- Endothelin Receptor(54)
- EP1 Receptor(2)
- EP4 Receptor(2)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(16)
- Galanin Receptors(11)
- Ghrelin Receptors(11)
- GHSR(20)
- GIP Receptor(5)
- Glucagon Receptor(54)
- Glucocorticoid Receptor(103)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(4)
- GPR119(11)
- GPR120(9)
- GPR35(10)
- GPR44(1)
- GPR55(11)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(57)
- LPA Receptor(12)
- LPL Receptor(64)
- LTD4 Receptor(1)
- mGluR (126)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(62)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(26)
- NK2 Receptors(7)
- NK3 Receptor(5)
- NOP Receptor(20)
- NPY Receptors(26)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(58)
- Oxytocin Receptors(22)
- P2Y Receptor(66)
- PACAP Receptors(7)
- PAF Receptors(7)
- Peptide Receptors(14)
- PGD2 Receptor(1)
- Prostaglandin Receptor(179)
- Prostanoid Receptors(25)
- Protease-Activated Receptors(9)
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(47)
- Sigma Receptor(62)
- Vasopressin Receptor(34)
- 17,20-lyase(4)
- Ras(180)
- Urotensin-II Receptor(10)
- VIP Receptors(6)
- EBI2/GPR183(7)
- TSH Receptor(12)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(11)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(8)
- CRFR(27)
- RGS Protein(5)
- Urotensin Receptor(7)
- Cholecystokinin Receptor(29)
- GPR139(4)
- mAChR(200)
- MCHR1 (GPR24)(17)
- Neurokinin Receptor(78)
- cGMP(27)
- GRK(5)
- GPR88(3)
- Amylin Receptor(9)
- Arrestin(10)
- Mas-related G-protein-coupled Receptor (MRGPR)(10)
- GCGR(13)
- GLP Receptor(27)
- Succinate Receptor 1(1)
- PTHR(3)
- Protease Activated Receptor (PAR)(6)
- Free Fatty Acid Receptor(5)
- Formyl Peptide Receptor (FPR)(7)
- Hydroxycarboxylic Acid Receptor (HCAR)(2)
- RXFP Receptor(3)
- Adhesion G Protein-coupled Receptors (AGPCRs)(1)
- Taste Receptor(1)
- GPR52(1)
Products Related to GPCR/G protein(3732)
- GC83111Glycopyrrolate-d 3 bromidePurity: >99.50%
Glycopyrrolate-d 3 (bromide) is deuterium labeled Glycopyrrolate.
- GC83131GR–14-3-3 stabilizer-1CAS: 271798-59-5Purity: >99.50%
GR-14-3-3 stabilizer-1 is a molecular glue stabilizer for the protein-protein interaction between 14‑3‑3 and glucocorticoid receptor (GR), and functions by stabilizing the GR‑14‑3‑3 protein-protein interaction.
- GC83132Granisetron-d 3CAS: 1224925-64-7Purity: >98.00%
Granisetron-d 3 is the deuterium labeled Granisetron.
- GC83137GRPR antagonist-1CAS: 3052544-28-9Purity: >99.50%
GRPR antagonist-1 is a potent gastrin releasing peptide receptor ( GRPR ) antagonist, having the cytotoxicity against certain cancer cells ( IC 50 of 4.97, 4.36 and 3.40 μM in PC3, Pan02 and HGC-27 cells, respectively).
- GC83157Harmane hydrochlorideCAS: 21655-84-5Purity: >99.50%
Harmane hydrochloride is a benzodiazepine receptor inhibitor ( IC 50 =7 μM), with IC 50 values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively.
- GC83212Hydrocortisone-d 2CAS: 1257650-73-9Purity: >98.50%
Hydrocortisone-d 2 is the deuterium labeled Hydrocortisone.
- GC83219Hyodeoxycholic acid-d 5Purity: >98.00%
Hyodeoxycholic acid-d 5 is the deuterium labeled Hyodeoxycholic acid.
- GC83244(R)-Igmesine hydrochloridePurity: >99.00%
(+)-Igmesine hydrochloride (JO1784) is an orally active and selective σ 1 receptor ligand with an IC 50 of 39 nM.
- GC83249ImapextideCAS: 3004569-93-8Purity: >98.00%
Imapextide is a glucagon-like peptide-1 ( GLP-1 ) receptor antagonist that can be used in hypoglycemia research [1] .
- GC83334Ketoconazole-d 4CAS: 1398065-75-2Purity: >98.00%
Ketoconazole-d 4 is the deuterium labeled Ketoconazole.
- GC83338Kisspeptin-10 (mouse, rat) TFAPurity: >99.50%
Kisspeptin-10 (mouse, rat) TFA is a potent vasoconstrictor and inhibitor of angiogenesis.
- GC83345KRAS G12D inhibitor 10CAS: 2648551-54-4Purity: >88.50%
KRAS G12D inhibitor 10 is a potent inhibitor of KRAS G12D.
- GC83346SetidegrasibCAS: 2821793-99-9Purity: >99.00%
Setidegrasib (ASP-3082) is a PROTAC KRAS degrader ( DC 50 : 37 nM).
- GC83348KRAS G12D inhibitor 3 TFACAS: 2757095-12-6Purity: >98.00%
KRAS G12D inhibitor 3 TFA is a KRAS G12D inhibitor with an IC 50 of <500 nM.
- GC83355L-796778 acetateCAS: 2922280-21-3Purity: >98.00%
L-796778 acetate is a selective agonist of the sst3 receptor.
- GC83373L-Ornithine-1,2,3,4,5- 13 C 5 hydrochlorideCAS: 943962-21-8Purity: >99.50%
L-Ornithine-1,2,3,4,5- 13 C 5 hydrochloride is the 13 C-labeled L-Ornithine hydrochloride.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC83111 | Glycopyrrolate-d 3 bromide | - | >99.50% | |
Glycopyrrolate-d 3 (bromide) is deuterium labeled Glycopyrrolate. | ||||
| GC83118 | GM-60186 | 3097453-30-7 | >99.00% | |
GM-60186 is a 5-HT receptor 2B (HTR2B) inhibitor with an IC 50 of 257 nM. | ||||
| GC83131 | GR–14-3-3 stabilizer-1 | 271798-59-5 | >99.50% | |
GR-14-3-3 stabilizer-1 is a molecular glue stabilizer for the protein-protein interaction between 14‑3‑3 and glucocorticoid receptor (GR), and functions by stabilizing the GR‑14‑3‑3 protein-protein interaction. | ||||
| GC83132 | Granisetron-d 3 | 1224925-64-7 | >98.00% | |
Granisetron-d 3 is the deuterium labeled Granisetron. | ||||
| GC83135 | GRL093-22 | 3113391-19-5 | >99.50% | |
GRL093-22 is a potent and selective G protein-coupled receptor kinase ( GRK ) inhibitor, with IC 50 s of 60 and 40 nM for GRK5 and GRK6, respectively. | ||||
| GC83136 | GS-2278 | 2750508-72-4 | >98.50% | |
GS-2278 is an LPAR1 (lysophosphatidic acid receptor 1) antagonist with potential for research in idiopathic pulmonary fibrosis ( IPF ) [1] . | ||||
| GC83137 | GRPR antagonist-1 | 3052544-28-9 | >99.50% | |
GRPR antagonist-1 is a potent gastrin releasing peptide receptor ( GRPR ) antagonist, having the cytotoxicity against certain cancer cells ( IC 50 of 4.97, 4.36 and 3.40 μM in PC3, Pan02 and HGC-27 cells, respectively). | ||||
| GC83156 | Harman- 13 C 2 , 15 N | 1189461-56-0 | - | |
Harman- 13 C 2, 15 N is 13 C and 15 N labeled Harmane. | ||||
| GC83157 | Harmane hydrochloride | 21655-84-5 | >99.50% | |
Harmane hydrochloride is a benzodiazepine receptor inhibitor ( IC 50 =7 μM), with IC 50 values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. | ||||
| GC83212 | Hydrocortisone-d 2 | 1257650-73-9 | >98.50% | |
Hydrocortisone-d 2 is the deuterium labeled Hydrocortisone. | ||||
| GC83219 | Hyodeoxycholic acid-d 5 | - | >98.00% | |
Hyodeoxycholic acid-d 5 is the deuterium labeled Hyodeoxycholic acid. | ||||
| GC83244 | (R)-Igmesine hydrochloride | - | >99.00% | |
(+)-Igmesine hydrochloride (JO1784) is an orally active and selective σ 1 receptor ligand with an IC 50 of 39 nM. | ||||
| GC83246 | IHCH-7086 | 2957888-70-7 | >98.50% | |
IHCH-7086 is a blood-brain barrier-permeable, partial β-arrestin-biased agonist of 5-HT 2A R with a K i of 12.59 nM. | ||||
| GC83249 | Imapextide | 3004569-93-8 | >98.00% | |
Imapextide is a glucagon-like peptide-1 ( GLP-1 ) receptor antagonist that can be used in hypoglycemia research [1] . | ||||
| GC83334 | Ketoconazole-d 4 | 1398065-75-2 | >98.00% | |
Ketoconazole-d 4 is the deuterium labeled Ketoconazole. | ||||
| GC83338 | Kisspeptin-10 (mouse, rat) TFA | - | >99.50% | |
Kisspeptin-10 (mouse, rat) TFA is a potent vasoconstrictor and inhibitor of angiogenesis. | ||||
| GC83339 | Kiss2 peptide acetate | - | - | |
Kiss2 peptide acetate is the acetate form of Kiss2 pepride. | ||||
| GC83344 | Olomorasib | 2771246-13-8 | >99.50% | |
Olomorasib is a potent inhibitor of KRAS G12C. | ||||
| GC83345 | KRAS G12D inhibitor 10 | 2648551-54-4 | >88.50% | |
KRAS G12D inhibitor 10 is a potent inhibitor of KRAS G12D. | ||||
| GC83346 | Setidegrasib | 2821793-99-9 | >99.00% | |
Setidegrasib (ASP-3082) is a PROTAC KRAS degrader ( DC 50 : 37 nM). | ||||
| GC83347 | QTX3034 | 2972625-49-1 | >98.00% | |
QTX3034 (KRAS G12D inhibitor 26) is a modulator of Kras, targeting Kras(G12D) with an IC 50 ≤ 100 nM [1] . | ||||
| GC83348 | KRAS G12D inhibitor 3 TFA | 2757095-12-6 | >98.00% | |
KRAS G12D inhibitor 3 TFA is a KRAS G12D inhibitor with an IC 50 of <500 nM. | ||||
| GC83355 | L-796778 acetate | 2922280-21-3 | >98.00% | |
L-796778 acetate is a selective agonist of the sst3 receptor. | ||||
| GC83373 | L-Ornithine-1,2,3,4,5- 13 C 5 hydrochloride | 943962-21-8 | >99.50% | |
L-Ornithine-1,2,3,4,5- 13 C 5 hydrochloride is the 13 C-labeled L-Ornithine hydrochloride. | ||||