GPCR/G protein
Research Areas
- Neuropeptide FF/AF Receptors(54)
- Neuropeptide S Receptor(3)
- GPBA Receptor(5)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- Formyl Peptide Receptors(11)
- 5-HT Receptor(432)
- Acetylcholine(28)
- Adenosine Deaminase(10)
- Adenosine Receptor(143)
- Adenosine Kinase(5)
- Adiponectin Receptor(3)
- Adrenergic Receptor(450)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(118)
- Bombesin Receptors(26)
- Bradykinin Receptors(30)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(121)
- Calcimimetic Agent(2)
- CaSR(28)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(98)
- Chemokine Receptors(23)
- CRF1 Receptors(10)
- CRF2 Receptors(3)
- CXCR(108)
- CysLT1 receptor(1)
- Endothelin Receptor(54)
- EP1 Receptor(2)
- EP4 Receptor(2)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(16)
- Galanin Receptors(11)
- Ghrelin Receptors(11)
- GHSR(20)
- GIP Receptor(5)
- Glucagon Receptor(54)
- Glucocorticoid Receptor(103)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(4)
- GPR119(11)
- GPR120(9)
- GPR35(10)
- GPR44(1)
- GPR55(11)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(57)
- LPA Receptor(12)
- LPL Receptor(64)
- LTD4 Receptor(1)
- mGluR (126)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(62)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(26)
- NK2 Receptors(7)
- NK3 Receptor(5)
- NOP Receptor(20)
- NPY Receptors(26)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(58)
- Oxytocin Receptors(22)
- P2Y Receptor(66)
- PACAP Receptors(7)
- PAF Receptors(7)
- Peptide Receptors(14)
- PGD2 Receptor(1)
- Prostaglandin Receptor(179)
- Prostanoid Receptors(25)
- Protease-Activated Receptors(9)
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(47)
- Sigma Receptor(62)
- Vasopressin Receptor(34)
- 17,20-lyase(4)
- Ras(181)
- Urotensin-II Receptor(10)
- VIP Receptors(6)
- EBI2/GPR183(7)
- TSH Receptor(12)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(11)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(8)
- CRFR(27)
- RGS Protein(5)
- Urotensin Receptor(7)
- Cholecystokinin Receptor(29)
- GPR139(4)
- mAChR(200)
- MCHR1 (GPR24)(17)
- Neurokinin Receptor(78)
- cGMP(27)
- GRK(5)
- GPR88(3)
- Amylin Receptor(9)
- Arrestin(10)
- Mas-related G-protein-coupled Receptor (MRGPR)(10)
- GCGR(13)
- GLP Receptor(27)
- Succinate Receptor 1(1)
- PTHR(3)
- Protease Activated Receptor (PAR)(6)
- Free Fatty Acid Receptor(5)
- Formyl Peptide Receptor (FPR)(7)
- Hydroxycarboxylic Acid Receptor (HCAR)(2)
- RXFP Receptor(3)
- Adhesion G Protein-coupled Receptors (AGPCRs)(1)
- Taste Receptor(1)
- GPR52(1)
Products Related to GPCR/G protein(3734)
- GC83355L-796778 acetateCAS: 2922280-21-3Purity: >98.00%
L-796778 acetate is a selective agonist of the sst3 receptor.
- GC83373L-Ornithine-1,2,3,4,5- 13 C 5 hydrochlorideCAS: 943962-21-8Purity: >99.50%
L-Ornithine-1,2,3,4,5- 13 C 5 hydrochloride is the 13 C-labeled L-Ornithine hydrochloride.
- GC83443Lumateperone metabolite 1CAS: 1469777-40-9Purity: >98.00%
Lumateperone metabolite 1 (Formula T) is a metabolite of Lumateperone [1] . Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist ( K i = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors ( K i = 32 nM), and a dopamine D1 receptor modulator [2] [3]
- GC83446Lurasidone-d 8 -1 hydrochloridePurity: >98.00%
Lurasidone-d 8 -1 (hydrochloride) is deuterium labeled Lurasidone (Hydrochloride).
- GC83562MevalonolactoneCAS: 19115-49-2Purity: >98.00%
Mevalonolactone is an intermediate metabolite in the eukaryotic mevalonate pathway, serving as the stable δ-lactone form of mevalonate with oral activity.
- GC83566Metoprolol-d 6 succinatePurity: >99.00%
Metoprolol-d 6 (succinate) is deuterium labeled Metoprolol (succinate).
- GC83573Milameline hydroiodidePurity: >96.00%
Milameline (CI 979; RU35926) hydroiodide is a nonselective, partical and orally active muscarinic receptor agonist that improves cognition.
- GC83577(-)-DihydroalprenololCAS: 59624-90-7Purity: >99.50%
(-)-Dihydroalprenolol (L-Dihydroalprenolol) is a β-adrenergic antagonist that inhibits the activity of β-adrenergic receptors.
- GC83600MMC(TMZ)-TOC TFAPurity: >95.00%
MMC(TMZ)-TOC TFA has high binding affinity and selectivity for somatostatin receptor subtype-2 ( SSTR2 ).
- GC83613MrgprX2 antagonist-3CAS: 2642174-19-2Purity: >99.50%
MrgprX2 antagonist-3 is an MrgprX2 antagonist extracted from patent WO2021092240A1, example E117.
- GC83614MRTX849 acidCAS: 2561529-96-0Purity: >99.50%
MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2.
- GC83663N-Formyl-MMYALFCAS: 863418-59-1Purity: >99.50%
N-Formyl-MMYALF is a potent mitochondrial N-formyl peptide (mtFP) that has the activity of depleting calcium ions in the endoplasmic reticulum.
- GC83713NNMT-IN-6 hydrochlorideCAS: 3031756-18-7Purity: >98.00%
NNMT-IN-6 hydrochloride is a selective nicotinamide N-methyltransferase ( NNMT ) inhibitor with an IC 50 of 1.41 μM and a K d of 5.55 μM.
- GC83723NOTA-P2-RM26CAS: 1446005-10-2Purity: >97.00%
NOTA-P2-RM26 is an antagonist of Bombesin analogs, and the gastrin-releasing peptide receptor ( GRPR/BB2 ) is a molecular target for prostate cancer visualization.
- GC83750Octopamine-d 3CAS: 111988-19-3Purity: >99.50%
Octopamine -d3 ((±)-p-Octopamine-d3) is the deuterated-labeled Octopamine.
- GC83756OlatorepatideCAS: 2675496-01-0Purity: >99.00%
Olatorepatide (Olatorepatidum) is a dual gastric inhibitory polypeptide ( GIP ) receptor and glucagon like peptide 1 ( GLP-1 ) receptor agonist, with antidiabetic effect [1] .
- GC83763ONO-AE 248CAS: 211230-67-0Purity: >98.00%
ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity.
- GC83778OveporextonCAS: 2460722-04-5Purity: >99.50%
Oveporexton (TAK-861) is an orally active and selective orexin receptor 2 (OX2R) agonist with an EC 50 of 2.5 nM.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC83355 | L-796778 acetate | 2922280-21-3 | >98.00% | |
L-796778 acetate is a selective agonist of the sst3 receptor. | ||||
| GC83373 | L-Ornithine-1,2,3,4,5- 13 C 5 hydrochloride | 943962-21-8 | >99.50% | |
L-Ornithine-1,2,3,4,5- 13 C 5 hydrochloride is the 13 C-labeled L-Ornithine hydrochloride. | ||||
| GC83397 | LB-102 | 2227154-23-4 | >98.50% | |
LB-102 is an orally active inhibitor of dopamine D 2, D 3, and 5-HT7 receptors, which can be used in research on schizophrenia and other psychiatric disorders [1] . | ||||
| GC83420 | Liraglutide-d 8 tetraTFA | - | - | |
Liraglutide -d 8 tetraTFA is deuterium labeled Liraglutide. | ||||
| GC83425 | LM11A-31 | 102562-74-3 | >99.50% | |
LM11A-31, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. | ||||
| GC83439 | LSP4-2022 | 1413405-33-0 | >98.00% | |
LSP4-2022 is a potent and brain-penetrant mGlu4 -selective orthosteric agonist, with an EC 50 of 0.11 μM. | ||||
| GC83443 | Lumateperone metabolite 1 | 1469777-40-9 | >98.00% | |
Lumateperone metabolite 1 (Formula T) is a metabolite of Lumateperone [1] . Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist ( K i = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors ( K i = 32 nM), and a dopamine D1 receptor modulator [2] [3] | ||||
| GC83446 | Lurasidone-d 8 -1 hydrochloride | - | >98.00% | |
Lurasidone-d 8 -1 (hydrochloride) is deuterium labeled Lurasidone (Hydrochloride). | ||||
| GC83562 | Mevalonolactone | 19115-49-2 | >98.00% | |
Mevalonolactone is an intermediate metabolite in the eukaryotic mevalonate pathway, serving as the stable δ-lactone form of mevalonate with oral activity. | ||||
| GC83566 | Metoprolol-d 6 succinate | - | >99.00% | |
Metoprolol-d 6 (succinate) is deuterium labeled Metoprolol (succinate). | ||||
| GC83572 | Mifepristone-d 3 | - | >97.50% | |
Mifepristone-d 3 is the deuterium labeled Mifepristone. | ||||
| GC83573 | Milameline hydroiodide | - | >96.00% | |
Milameline (CI 979; RU35926) hydroiodide is a nonselective, partical and orally active muscarinic receptor agonist that improves cognition. | ||||
| GC83577 | (-)-Dihydroalprenolol | 59624-90-7 | >99.50% | |
(-)-Dihydroalprenolol (L-Dihydroalprenolol) is a β-adrenergic antagonist that inhibits the activity of β-adrenergic receptors. | ||||
| GC83600 | MMC(TMZ)-TOC TFA | - | >95.00% | |
MMC(TMZ)-TOC TFA has high binding affinity and selectivity for somatostatin receptor subtype-2 ( SSTR2 ). | ||||
| GC83613 | MrgprX2 antagonist-3 | 2642174-19-2 | >99.50% | |
MrgprX2 antagonist-3 is an MrgprX2 antagonist extracted from patent WO2021092240A1, example E117. | ||||
| GC83614 | MRTX849 acid | 2561529-96-0 | >99.50% | |
MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2. | ||||
| GC83663 | N-Formyl-MMYALF | 863418-59-1 | >99.50% | |
N-Formyl-MMYALF is a potent mitochondrial N-formyl peptide (mtFP) that has the activity of depleting calcium ions in the endoplasmic reticulum. | ||||
| GC83713 | NNMT-IN-6 hydrochloride | 3031756-18-7 | >98.00% | |
NNMT-IN-6 hydrochloride is a selective nicotinamide N-methyltransferase ( NNMT ) inhibitor with an IC 50 of 1.41 μM and a K d of 5.55 μM. | ||||
| GC83714 | NNMT-IN-7 | 1973504-60-7 | >98.00% | |
NNMT-IN-7 is a nicotinamide N-methyltransferase ( NNMT ) inhibitor with an IC 50 of 505.7 μM against human targets. | ||||
| GC83723 | NOTA-P2-RM26 | 1446005-10-2 | >97.00% | |
NOTA-P2-RM26 is an antagonist of Bombesin analogs, and the gastrin-releasing peptide receptor ( GRPR/BB2 ) is a molecular target for prostate cancer visualization. | ||||
| GC83750 | Octopamine-d 3 | 111988-19-3 | >99.50% | |
Octopamine -d3 ((±)-p-Octopamine-d3) is the deuterated-labeled Octopamine. | ||||
| GC83756 | Olatorepatide | 2675496-01-0 | >99.00% | |
Olatorepatide (Olatorepatidum) is a dual gastric inhibitory polypeptide ( GIP ) receptor and glucagon like peptide 1 ( GLP-1 ) receptor agonist, with antidiabetic effect [1] . | ||||
| GC83763 | ONO-AE 248 | 211230-67-0 | >98.00% | |
ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity. | ||||
| GC83778 | Oveporexton | 2460722-04-5 | >99.50% | |
Oveporexton (TAK-861) is an orally active and selective orexin receptor 2 (OX2R) agonist with an EC 50 of 2.5 nM. | ||||