Resolvin D1 methyl ester (Synonyms: 17(S)-Resolvin D1 methyl ester, RvD1 methyl ester) |
| Catalog No.GC41230 |
El éster metÍlico de Resolvin D1 (éster metÍlico de RvD1) es el éster metÍlico de Resolvin D1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 937738-63-1
Sample solution is provided at 25 µL, 10mM.
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Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM. RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
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