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Rolitetracycline (Synonyms: Pyrrolidinylmethyltetracycline, SQ 15,659)

Catalog No.GC18287

La rolitetraciclina, un derivado de la tetraciclina, es un antibiÓtico de amplio espectro.

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Rolitetracycline Chemical Structure

Cas No.: 751-97-3

Tamaño Precio Disponibilidad Cantidad
5mg
170,00 $
Disponible
25mg
596,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products
Rolitetracycline is a tetracycline antibiotic with bacteriostatic activity at low concentrations (7.8 μg/ml) and bactericidal activity at high concentrations (15.6 μg/ml) against E. coli. It has additive and synergistic effects with penicillin and cephalothin, respectively, in vitro against 34 E. coli and S. aureus strains. Rolitetracycline is also active against P. falciparum strains (IC50s = 45-208 μM) that are susceptible and resistant to chloroquine . It also reduces amyloid-β (1-40) (Aβ40) fibrilization (IC50 = 59 μM in an immune assay) and completely inhibits Aβ40-induced cellular toxicity at a concentration of 20 μM.

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Average Rating: 5 ★★★★★ (Based on Reviews and 20 reference(s) in Google Scholar.)

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