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Rolitetracycline (Synonyms: Pyrrolidinylmethyltetracycline, SQ 15,659)

カタログ番号GC18287

テトラサイクリンの誘導体であるロリテトラサイクリンは、広域抗生物質です。

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Rolitetracycline 化学構造

Cas No.: 751-97-3

サイズ 価格 在庫数 個数
5mg
$170.00
在庫あり
25mg
$596.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products
Rolitetracycline is a tetracycline antibiotic with bacteriostatic activity at low concentrations (7.8 μg/ml) and bactericidal activity at high concentrations (15.6 μg/ml) against E. coli. It has additive and synergistic effects with penicillin and cephalothin, respectively, in vitro against 34 E. coli and S. aureus strains. Rolitetracycline is also active against P. falciparum strains (IC50s = 45-208 μM) that are susceptible and resistant to chloroquine . It also reduces amyloid-β (1-40) (Aβ40) fibrilization (IC50 = 59 μM in an immune assay) and completely inhibits Aβ40-induced cellular toxicity at a concentration of 20 μM.

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Average Rating: 5 ★★★★★ (Based on Reviews and 20 reference(s) in Google Scholar.)

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