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S-(2,4-Dinitrophenyl)-Glutathione (Synonyms: Dinitrophenyl-S-Glutathione)

Catalog No.GC18514

S-(2,4-Dinitrophenyl)-glutathione is a substrate for glutathione-S-transferase with a kinetic dissociation constant of 7 uM.

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S-(2,4-Dinitrophenyl)-Glutathione Chemical Structure

Cas No.: 26289-39-4

Tamaño Precio Disponibilidad Cantidad
1mg
68,00 $
Disponible
5mg
303,00 $
Disponible
10mg
503,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

S-(2,4-Dinitrophenyl)-glutathione is a substrate for glutathione-S-transferase with a kinetic dissociation constant of 7 uM. [1]  In vitro, it is transported by multidrug resistance protein 1 (MDR1) and MDR3, which are transporters that confer resistance to some chemotherapeutics.[2] 

Reference:
[1]. Schramm, V.L., McCluskey, R., Emig, F.A., et al. Kinetic studies and active site-binding properties of glutathione S-transferase using spin-labeled glutathione, a product analogue. J. Biol. Chem. 259(2), 714-722 (1984).
[2]. Zeng, H., Liu, G., Rea, P.A., et al. Transport of amphipathic anions by human multidrug resistance protein 3. Cancer Res. 60(17), 4779-4784 (2000).

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