(S,R,S)-AHPC-Me-C5-COOH |
Catalog No.GC63494 |
(S,R,S)-AHPC-Me-C5-COOH es un conjugado enlazador-ligando de ligasa E3 sintetizado que incorpora un ligando VHL y un enlazador. (S,R,S)-AHPC-Me-C5-COOH se puede utilizar en PROTAC DT2216.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2229976-21-8
Sample solution is provided at 25 µL, 10mM.
(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604)[1].
DT2216 is a selective B-cell lymphoma extra large (BCL-XL) PROTAC degrader[1].
[1]. Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.
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