Sulfo-SMCC sodium |
| Catalog No.GC30045 |
El sulfo-SMCC sÓdico es un reticulante de ADC no escindible, heterobifuncional y de uso comÚn que lleva grupos éster de N-hidroxisuccinimida (NHS) y maleimida para reaccionar con aminas primarias y grupos sulfhidrilo, respectivamente.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 92921-24-9
Sample solution is provided at 25 µL, 10mM.
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Sulfo-SMCC sodium is a commonly used hetero-bifunctional crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time[1].
[1]. Prabhune M, et al. Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro. PLoS One. 2016 Aug 25;11(8):e0161623.
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