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SUVN-911

Catalog No.GC39575

SUVN-911 es un antagonista del receptor de acetilcolina α4β2 neuronal nicotÍnico potente, selectivo, penetrado en el cerebro y biodisponible por vÍa oral, con una Ki de 1,5 nM.

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SUVN-911 Chemical Structure

Cas No.: 2414674-71-6

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL DMSO)
347,00 $
Disponible
5mg
315,00 $
Disponible
10mg
522,00 $
Disponible
50mg
1.485,00 $
Disponible
100mg
2.295,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SUVN-911 is a potent, selective, brain penetrated and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist, with a Ki of 1.5 nM. SUVN-911 has antidepressant activity[1].

[1]. Ramakrishna Nirogi, et al. Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression. J Med Chem. 2020 Mar 26;63(6):2833-2853.

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Average Rating: 5 ★★★★★ (Based on Reviews and 14 reference(s) in Google Scholar.)

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