TAK960 |
Catalog No.GC10773 |
TAK960 es un inhibidor selectivo de la cinasa tipo polo 1 (PLK1), disponible por vía oral, con una IC50 de 0,8 nM. TAK960 también muestra actividades inhibitorias contra PLK2 y PLK3, con IC50 de 16,9 y 50,2 nM, respectivamente. TAK960 inhibe la proliferación de múltiples líneas celulares de cáncer y exhibe una eficacia significativa contra múltiples xenoinjertos tumorales.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1137868-52-0
Sample solution is provided at 25 µL, 10mM.
Reference:
[2]. Inoue M, et al. PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase. Sci Rep. 2015 Oct 27;5:15666.
Average Rating: 5
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