ZAP 180013 |
| Catalog No.GC50577 |
ZAP 180013 es un inhibidor de la proteína quinasa 70 asociada a la cadena zeta (ZAP-70) con una IC50 de 1,8 μM.
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Cas No.: 873080-25-2
Sample solution is provided at 25 µL, 10mM.
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Zeta-chain-associated protein kinase 70 (Zap70) inhibitor (IC50 = 1.8 μM in fluorescence polarization assay). Inhibits the interaction of Zap70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs), within the T-cell antigen receptor (TCR) signaling pathway.
Visperas et al (2017) Identification of inhibitors of the association of ZAP-70 with the T-cell receptor by high-throughput screen. SLAS.Discov. 22 324 PMID:27932698
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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