4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid (sodium salt) (Synonyms: 4-MUNANA, Neu5Ac-α-4MU, Sodium 2-(4-methylumbelliferyl)-N-acetylneuraminate) |
| رقم الكتالوجGC42448 |
4-Methylumbelliferyl-N-acetyl-α ؛ -D-Neuraminic Acid (ملح الصوديوم) عبارة عن ركيزة فلورية تستخدم لفحص نشاط النورامينيداز.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 76204-02-9
Sample solution is provided at 25 µL, 10mM.
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4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.
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